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By incorporating pAF residue at position V15 into the hydrophobic pore at dimer interface of the multidrug resistance regulator from Lactococcus lactis (LmrR), 231 the catalytic activity of the aniline side chain in hydrazone and oxime formation reactions was enhanced, outperforming wild-type LmrR, aniline and more reactive aniline derivatives

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X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II